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Some users have tried intermittent dosing patterns (every 2 weeks instead of weekly, or 6 weeks on followed by 2 weeks off)

Nat Metab 2(3):142148 Shi Q, Wang Y, Hao Q et al (2024) Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials

Network Meta-Analysis: An Introduction for Clinicians

While the most common side effects are digestive, some people still ask: Can semaglutide cause anxiety