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Pharmacological preparations for intravenous therapy are generally more expensive than the corresponding oral medications, and the initially high plasma level achieved with some drugs may cause undesirable side effects

This makes it especially important for people with PCOS to discuss both their treatment goals and contraception needs with their healthcare provider when considering GLP-1 agonists

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Bhatt DL, Szarek M, Pitt B, et al

Understanding these differences is essential when you are thinking about switching from Tirzepatide to Retatrutide