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Personal and family medical history, especially with heart disease

Mechanisms of benefit may include both weight reduction and direct pharmacological effects, such as reduced cerebrospinal fluid secretion via GLP-1 receptors in the choroid plexus, and anti-inflammatory/neuroprotective actions in the brain

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2007;13(2):S146-52

Specifically, the FDA considered claims that compounded products are generic versions or contain the same active ingredient as FDA-approved GLP-1 drugs are false or misleading