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Using immunofluorescence and confocal microscopy, we observed prominent mitochondrial but minimal nuclear localization of catalytic subunit of the pyruvate dehydrogenase complex (PDHe1) (Supplemental Figure 6A)
It is important to note that these studies and related use of GLP-1 focus on reducing the severity and frequency of alcohol use and binge drinking
These studies explore whether combining signaling mechanisms influencing satiety, gastric emptying, and glucose regulation produces distinct biologic responses compared with individual agents
36 JangS
Design strategies, advances and future perspectives of colon-targeted delivery systems for the treatment of inflammatory bowel disease