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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023

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I no longer have high cholesterol, and weight loss has significantly reduced my knee and back pain

Its expansion and/or activation can protect against diet-induced obesity

3.1 Age and sex distribution PD predominantly affects individuals over the age of 60, with incidence rising sharply after the age of 70

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