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Variants in GLP1R rs6923761, GIPR rs1800437, FTO rs9939609, and MC4R rs17782313 can support more informed provider conversations about personalized treatment expectations, though they do not predict exact outcomes

Coverage for off-label weight-loss use is rare

Roughly half of the patients had taken GLP-1 medications, including 1,776 who received the newer, more effective drugs semaglutide, sold as Ozempic and Wegovy by Novo Nordisk, and tirzepatide, sold as Mounjaro and Zepbound by Eli Lilly

GLP-1s may lower blood pressure by facilitating weight loss and by acting on the kidneys and blood vessels

Eid RA, Zaki MSA, Alaa Eldeen M, Alshehri MM, Shati AA, El-Kott AF

Black Spider Cloma Pharma