Use of a GLP-1 drug for one to three years was associated with a higher risk of thyroid cancer overall (hazard ratio about 16) and of medullary thyroid cancer specifically (about 18)
Bertolini A, Ferrari A, Ottani A, Guerzoni S, Tacchi R, Leone S (2006)
Some people may experience mild digestive changes as their liver function improves
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Identity: synthetic 16-amino-acid peptide
These findings provide some reassurance regarding the general cancer safety profile of this drug class in human populations, though the limited duration of most studies must be acknowledged when interpreting these results