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inspect for discolouration or particles (note that B12 solution is normally red) Prepare the injection site common sites include the thigh (vastus lateralis) for both IM and SC injections, or the ventrogluteal area for IM administration if trained to use this site Administration technique: Clean the injection site with an alcohol wipe and allow to dry completely

doi: 10.1056/NEJMoa2511774

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Study screening and selection procedure is summarized in Fig