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Thus, A 2A R antagonists block the effects of adenosine and facilitate D 2 R agonist effects on lowering cAMP levels and then dampens PKA activity, which may result in neuroprotective effects

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Exp Cell Res 317(9):12391245 Al-Badri G, Leggio GM, Musumeci G, Marzagalli R, Drago F, Castorina A (2018) Tackling dipeptidyl peptidase IV in neurological disorders