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Does the oral spray require refrigeration

To minimise these effects, take metformin with or immediately after meals, and consider extended-release formulations if standard metformin causes significant digestive upset

Pernicious anaemia and deficiency with neurological involvement require more intensive treatment with alternate-day injections until improvement, followed by lifelong maintenance

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These smart agents minimize off-target toxicity while maximizing reactive oxygen species production at disease sites, thereby enhancing therapeutic efficacy and safety [74]

W.KroemerG.et al (2017)