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Recent bioinformatics studies revealed that HAS2 is associated with immune cell activation, chemotaxis, and cytokine release in individuals with POP and is implicated in ECM functions

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This data clearly demonstrates that there is no change to the observed kinetics when excess SmTrx is combined with SmTGR U597S in the presence of limiting NADPH, establishing that the C596-U597 disulfide is required for SmTrx reduction

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