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Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein

The Forms of Glutathione Glutathione exists in two primary forms: Reduced Glutathione (GSH), the active form, and oxidized Glutathione (GSSG), the inactive form

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The disruption mechanisms of oxidative stress include oxidative damage to cellular components (protein oxidation, lipid peroxidation, and DNA damage), activation of matrix metalloproteinases, cytoskeleton reorganization, modulation of tight junction proteins, and upregulation of inflammatory mediators [81, 86, 87]