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Osimertinib, surgery, and radiation therapy in treating patients with stage IIIB or IV non-small cell lung cancer with EGFR mutations, NORTHSTAR study

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To account for the extent of multiple inclusion of primary studies (overlaps) in the included systematic reviews, the Corrected Covered Area (CCA) formula was used: where N is the sum of the included primary studies, accounting for double counting, r is the number of distinctly indexed primary studies, and c is the number of included systematic reviews (22)

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