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Redox biology in neurodegenerative disorders

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ACS Chem Biol 14(12):25952605 Ferri E, Le Thomas A, Wallweber HA, Day ES, Walters BT, Kaufman SE et al (2020) Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

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In contrast, a study of first-episode cases reported elevated glutathione in medial temporal lobes [27] raising the possibility that glutathione abnormalities might vary with phase of illness

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Glutathione is a natural antioxidant made in the body

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