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They enhance the intestinal microbiota by increasing beneficial bacteria and SCFAs, while protecting the brain by inhibiting amyloid- accumulation, thereby improving both gut health and cognitive function [81,87]

The plateau is partly a peripheral problem

Representative tissue specimens were embedded in paraffin, sectioned at 4 m, stained with hematoxylin and eosin (H&E), and evaluated by light microscopy using an Olympus 71 digital camera and an Olympus BX51 microscope (Japan) acquiring digital images saved as uncompressed 24-bit RGB TIFF files

For the control of blood glucose, specific endocrine cells in the pancreas detect excess glucose (the stimulus) in the bloodstream

Mechanism involves GH-driven lipolysis in visceral depots without disproportionate effects on subcutaneous fat

Thus, resistance to anti-VEGF drugs in advanced-stage breast cancer may be explained by the dominance of FGF-2 and other pro-angiogenic factors in such stage of the disease (Schneider and Miller, 2005)