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This is because obesity is linked to worse outcomes in people with breast cancer, particularly in postmenopausal women

While there has been no clear association with certain psychiatric side effects, such as depression or suicidal ideation in research-based 31 or real-world 32 samples, the potential modulation of reward pathways by these drugs necessitates vigilant monitoring in patients with psychiatric histories, particularly in the setting of treatment with a medication that can substantially modulate the response of appetitive neurocircuitry to natural rewards such as food and water

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Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis

JCI Insight 2021;6