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While many wellness peptides influence growth hormone levels or target specific tissue repair, MOTS-C is unique because it originates in the mitochondrial genome

The critical role of the redox-sensitive transcription factor Nrf2 is highlighted by findings that Nrf2-deficient mice exhibit increased susceptibility to prolonged, noise-induced tinnitus-like behavior, accompanied by heightened microglial activation and neuroinflammation (Yang et al., 2025)

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Vitamin D, acting through widely distributed vitamin D receptors (VDRs) and local activation within the brain, modulates neurotrophin expression, neurotransmitter systems, calcium homeostasis, and immune responses, with deficiency linked to increased risk of cognitive impairment and neurodegenerative pathology (11, 12)

Sexual wellness: PT-141 (Bremelanotide) works through the brain to support libido and arousal