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in addition, higher circulating IGF-1 has been linked with increases in MPS, muscle free fatty acid utilization, and improvements insulin sensitivity (Kraemer et al., 2017), which may explain its often linked importance in exercise training adaptations
It functions as a cofactor for methylmalonyl-CoA mutase in mitochondrial metabolism
doi: 10.1515/zpch-1923-10615
Napoli PE, Braghiroli M, Iovino C, Demarinis G, Fossarello M
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