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Mazdutide works by activating two receptors at once: GLP-1, which suppresses appetite and slows gastric emptying, and the glucagon receptor, which increases energy expenditure and supports hepatic fat metabolism

Robert Popovian 01:24 Hey, Conner, lets get into this episode

Alluvi Retatrutide vs Current GLP-1 Injections Feature Alluvi Retatrutide (Research) Wegovy Mounjaro Receptors targeted GLP-1 + GIP + Glucagon GLP-1 only GLP-1 + GIP Average Weight Loss ~24 % (48 weeks) ~15 % ~21 % Energy Expenditure Higher Moderate Moderate Regulatory Status UK Investigational Approved Approved (private) Safety Profile and Side Effects Observed Typical short-term effects reported in trials: Nausea, constipation or diarrhoea Mild fatigue Temporary appetite changes No long-term data exist yet for higher doses such as 40 mg