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They are not FDA-approved
author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law
This is especially important for patients with absorption issues such as those with digestive conditions, low stomach acid (common with aging), or MTHFR gene variants who cannot adequately absorb B12 from food or oral supplements
And by doing that, it helps preserve NAD + (key energy carrying molecule), SAM (universal methyl donor), and the downstream processes that depend on them
Clinical practitioners who administer this combination report side effect profiles consistent with each compound used individually
Pernicious anemia is a type of anemia that results when a persons stomach cells do not create intrinsic factor, and without this the body is unable to absorb vitamin B12
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