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Palazzuoli, V., Mondillo, S., Faglia, S., D'Aprile, N., Camporeale, A., and Gennari, C

The baseline characteristics of the critically ill patients were comparable between the two groups ( Table 1 )

No major trial has demonstrated superior results from splitting weekly doses into smaller, more frequent injections

[cited]

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Overall, HT pathogenesis results from a complex interplay between innate and adaptive immunity, where breakdowns in tolerance, skewed Th1/Th17/Treg balance, and persistent autoantibody production sustain chronic inflammation and irreversible thyroid destruction