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The trial met all primary and key secondary endpoints, demonstrating significant improvements in both weight loss and pain reduction at 68 weeks

Some patients even end up needing less thyroid medication, but that should only be done with medical guidance

"If newly identified safety signals are identified, the FDA will determine what actions are appropriate after a thorough review of the body of evidence," spokeswoman Chanapa Tantibanchachai said in a statement

For example: Long-acting (often weekly) GLP-1 drugs These provide steadier levels over time and can improve both fasting and overall blood sugar control

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H2 blockers and proton pump inhibitors are commonly used alongside GLP-1 therapy with good safety data