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[DOI] [PMC free article] [PubMed] [Google Scholar] Veltri C, & Grundmann O (2019)

Because gut inflammation is linked to many chronic diseases, this may be one of the mechanisms behind the broader health benefits researchers are seeing

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As sDPP4 is an adipokine upregulated in obesity and T2DM that triggers IR and metabolic complications (4, 5), it might be speculated that the beneficial effects of DPP4 inhibitors would be higher in those early phases of the metabolic disorders previous to the development of established cardiovascular disease

The difference is the delivery method (vial and syringe versus pre-filled pen) and the absence of brand-name marketing and patent premiums

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