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Preclinical work, predominantly from Sikiric and colleagues, has examined its activity in gastrointestinal ulcer models, tendon and ligament repair models, and endothelial/VEGF (vascular endothelial growth factor)-linked angiogenesis pathways

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and HGF) [23] or bone marrow stromal cells with the application of cyclosporine, minocycline, and methylprednisolone [24])

2007, 61: 111-10.1038/sj.ejcn.1602490