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GLP-1 Medications: What the Evidence Shows Clinical trials of semaglutide and tirzepatidetwo leading GLP-1 receptor agonistsshow weight loss of 10 to 22 percent over 68 weeks, with significant improvements in blood sugar control and cardiovascular markers

What Are Semaglutide and Tirzepatide and How Do They Work

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Wegovy , containing semaglutide, is another effective GLP-1 receptor agonist approved for chronic weight management