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Irisin has been shown to play key roles in regulating metabolism, reducing oxidative stress, decreasing inflammation, preventing apoptosis, and improving mitochondrial dysfunction ( TABLE 2 Experimental models of the effects of irisin on depression

This inhibition necessitates the activation of MUFAs by acyl-coenzyme A synthetase long-chain family member 3 (ACSL3) [37]

Morgan AS, Ciaccio PJ, Tew KD and Kauvar LM

Consideration was also given to the biological context, leading to a classification of the identified molecules reflected in the tags associated with each compound in the manually annotated table

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It assists in the control of the melanin production and minimisation of the excess pigmentation