125 Additionally, CSCs interact with their microenvironment through secreted factors, such as cytokines and extracellular vesicles (e.g., exosome-derived miRNAs), further expanding the repertoire of potential biomarkers 126 (Fig
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Additionally, there is a controlling role of the pentadecapeptide BPC 157 against the tumor-promoting effects of many growth factors and peptides (Sikiric et al., 2018) as well as counteracting harmful escape from the initial healing effect (i.e., angiogenesis)