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TMABA is then dehydrogenated into gamma-butyrobetaine in an NAD + -dependent reaction, catalyzed by TMABA dehydrogenase

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Increased HIF-1 activity stimulates ASCT2 transcription alongside other amino acid transporters to boost glutamine uptake which supports cell survival and proliferation within hypoxic tumor settings

2006;291(5 ): E11005

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Reference lists of included studies and relevant reviews were screened manually to identify additional eligible studies