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The NTS is the main source of endogenous GLP-1 within the brain (Holt et al., 2019)

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J., Cardiovascular Effects of Dipeptidyl Peptidase4 Inhibitors: From Risk Factors to Clinical Outcomes, Postgraduate Medicine 125, no

Here are some common side effects of methylfolate that you may experience: Headache Migraine Rashes Irritability Restlessness Joint discomfort Muscle discomfort Poor sleep Low mood If you experience any of these side effects, it might be a sign that the dose of methylfolate youre taking is too high for your body at this moment