are supported by grants from the FWF SFB Lipid Hydrolysis (grant number F7302) and SFB Immunometabolism (grant number F83), respectively
B12 deficiency can affect anyone, regardless of dietary choices
11 In addition, in the treatment of PF, FOXO4DRI may reduce the risk of cancer progression and metastasis by eliminating senescent cells, which have been demonstrated to contribute to cancer metastasis and relapse
They will check vitamin B12 levels and how the patient is doing to adjust the treatment as needed
References Cell Metabolism (2015) The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (Lee C, Zeng J, Drew BG, et al.) Journal of Translational Medicine (2023) Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging (Wan W, Zhang L, Lin Y, et al.) Journal of Molecular Medicine (2019) MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction (Lu H, Wei M, Zhai Y, et al.) Nature Communications (2021) MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis (Reynolds JC, Lai RW, Woodhead JST, et al.) Frontiers in Physiology (2023) Role of MOTS-c in the regulation of bone metabolism (Yi X, Hu G, Yang Y, et al.) Cognitive Vitality Reports (2021) MOTS-c (Cognitive Vitality Profile) Alzheimers Drug Discovery Foundation (ADDF) USADA Spirit of Sport (2023) What is the MOTS-c peptide
It remains available as a research compound
