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Additionally, they influence fibroblast behavior by enhancing proliferation, migration, and adhesion while inhibiting apoptosis-related pathways involving Bax, Bcl-2, caspase-3, and caspase-9

This triagonist profile creates research opportunities that single agonists and dual agonists cannot replicate, particularly in studies examining energy homeostasis, metabolic regulation, and receptor interaction cascades

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Beyond therapeutic innovation, however, the congress highlighted a broader transformation in healthcare: the growing importance of patient-centered care, the implementation of the new European Union Health Technology Assessment (HTA) Regulation, and the increasing role of Real-World Data (RWD) and Real-World Evidence (RWE) in bridging the gap between clinical trial results and outcomes achieved in everyday clinical practice