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In SURPASS trials, patients on metformin plus tirzepatide achieved HbA1c reductions of 2.0-2.5%, with many reaching HbA1c targets below 5.7% (normal range)

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J Biomed Sci (2017) 24(1):76

The distinction matters enormously because each phenomenon requires a different reset strategy

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Consumer demand is accelerating, oral formulations are nearing the market, Medicare negotiations are set to reshape pricing, pivotal trial readouts in Alzheimers and chronic kidney disease could unlock entirely new indications, and the market is forecast to top $100 billion by 2030