With semaglutide, this happens after about 4 to 5 weeks of consistent weekly dosing
This change in body composition intensifies the risk of diabetes, cardiovascular disease, dyslipidemia (abnormal levels of lipids in the blood) and metabolic dysfunction-associated steatotic (fatty) liver disease
There's also something to be said for the format itself: powder mixed into liquid arrives in your gut already hydrated and dispersed no breakdown required before it can start doing its job
Possible long-term risks include: Gallstones or gallbladder inflammation, especially with rapid weight loss Pancreatitis, which is inflammation of the pancreas Kidney stress or acute kidney injury linked with dehydration from vomiting or diarrhoea Severe constipation or worsening digestive symptoms Delayed stomach emptying or gastroparesis-like symptoms Possible worsening of diabetic retinopathy in some people with type 2 diabetes, especially if blood sugar improves very quickly Increased heart rate in some people Allergic reactions, such as swelling, rash, itching, or breathing difficulty Mood changes or suicidal thoughts, which need immediate medical attention Loss of lean muscle mass if weight loss happens without enough protein and strength training Facial volume loss due to rapid weight loss, sometimes called Ozempic face, although this can happen with rapid weight loss from any cause Some GLP-1 medicines carry a warning related to thyroid C-cell tumours seen in animal studies
Both ileus and bowel obstruction are medical emergencies
First, every single region requires prior authorization
