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Research published since the STEP trials shows that adequate protein intake (1.0 to 1.6 grams per kilogram of body weight daily) combined with resistance training two to three times per week can significantly reduce lean mass loss, potentially lowering it to 20 to 25 percent of total weight lost

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Animal models have shown that estradiol increases energy expenditure through increased thermogenesis and lipolysis of BAT

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While convenient, skipping pre-treatment labs can delay identification of underlying thyroid dysfunction, kidney impairment, or metabolic abnormalities that may influence medication safety and dosing