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2018;41(Suppl 1):S86104

employed a diet-induced NASH mouse model to compare the efficacy of cotadutide (a dual GLP-1/GCG agonist) against liraglutide (selective GLP-1 receptor agonist) and pair-fed controls

Glucagon-like peptide-1 receptor agonists induce glucose-dependent insulin secretion, beta-cell protection, and other extraglycemic benefits such as weight loss and improvement in markers of cardiovascular risk

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Therefore, more extensive randomized controlled trials (RCTs) are essential to elucidate these relationships and inform clinical practice