That's exactly the purpose of working with a licensed healthcare provider, not just buying vitamin supplements at the grocery store
Collagen is a more permanent filler, and we tend to avoid is because our bodies are not permanent things they change over time, and so it can be very difficult to create a result with these that will not look unnatural as the body around it changes with time
Gmez-Donoso C, Snchez-Villegas A, Martnez-Gonzlez MA, Gea A, Mendona RD, et al
An NNMT inhibitor like 5-amino-1MQ could help by stimulating the synthesis of NAD+, a vital cofactor in the electron transport chain
A few studies in humans have been performed with AOD 9604
A permanent solution is obtained by lower eyelid surgery, by everting and tightening the eyelid