The 2022 List was approved by WADAs Executive Committee (ExCo) during its meeting on 14 September 2021 and comes into force on 1 January 2022
Researchers get fast onset without the drawbacks of oral or injectable formats
and if shelf life is 28 days, and I am to inject this into his subq once a week
The sequence contains four proline residues that contribute to its conformational stability
The authors administered oral Dihexa to APP/PS1 transgenic mice (a standard amyloidopathy model of Alzheimers disease) and showed that brain AngIV levels were elevated relative to wild-type after Dihexa administration, that spatial learning and memory were restored on Morris water maze testing, that hippocampal neuronal density and synaptophysin protein expression were preserved, that astrocyte and microglial activation were reduced, and that pro-inflammatory cytokines (IL-1, TNF-) decreased while anti-inflammatory IL-10 increased
Protection against ongoing injury from NSAIDs, corticosteroids, and other damaging agents extends the peptides utility
