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These findings strengthen the hypothesis that Epitalons chronobiotic activity extends beyond hormonal stimulation because it may also preserve the structural and cellular integrity of the pineal gland as we age [57]

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This is not listed in the official prescribing information and the cause is not fully understood

Fasting triggers numerous hormonal adaptations that do not happen with simple caloric reduction

This close proximity facilitates autocatalytic activation of caspase-1, which is the key effector protease of the inflammasome complex

although this patient developed hepatotoxicity and was treated with NAC and dialysis, it was suggested that this case was less clinically severe than would be expected in an adult [51]