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Herrera-Gomez F, Asensio-Gonzalez M, Gonzalez-Lopez A, Alvarez FJ
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Interestingly, the GLP-1 receptor agonist, dulaglutide, and the dual GLP-1 and GIP receptor agonist, tirzepatide, are both characterized by a strong delayed gastric emptying upon a single dose administration, but the effect tends to subside as gastric emptying tachyphylaxis is observed after several weeks of treatment
They also tend to decrease appetite and slow digestion
10.1056/NEJMoa1111065 207 WangJ
These results suggest the potential of H8 to ameliorate lipid metabolism abnormalities associated with 11-HSD1 overexpression
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