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Beyond appetite regulation, GLP-1 plays a critical role in blood sugar management

There can be no assurance that actual results will not materially differ from expectations

For manufacturers, the OSD form offers an exit ramp away from complex aseptic fill-finish operations, which would enable greater flexibility while reducing operational costs

Concurrent medications must be considered, particularly for oral semaglutide, which requires a 30-minute separation from other medications and food

The key is having a clinician experienced with pediatric obesity guiding that decision, rather than extrapolating from adult guidelines

Giblett JP, Clarke SJ, Dutka DP, Hoole SP