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Jurkat cells were maintained in RPMI media (Gibco) containing 2 mM glutamine, 10% fetal bovine serum, 1% penicillin and streptomycin

In a specific embodiment the formulation or composition provides a therapeutically effective amount of at least one otic agent at the site of disease with essentially no systemic exposure

Our findings also underscore the crucial role of central redox mechanisms, particularly in the mPFC, in mediating the pathophysiological effects of THC

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