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This nuclear presence of FOXO4 seems to be involved in maintaining the viability of senescent cells by possibly modulating downstream senescence-associated pathways, detailed by changes in p53, Ser15-phospho-p53, and p21 protein levels

The fusions were purified using a CaptureSelect FcXL affinity matrix (ThermoFisher) packed in a 5 ml column (Repligen) per the manufacturer recommendations

doi: 10.1016/j.heliyon.2023.e19763 202 RodriguezJBystrynJC

Cellular responses induced after contact with helicobacter pylori

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