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Whether the acute meal terminating effects of bupropion documented in animal studies could be translated into long-term weight loss efficacy in humans was addressed by three clinical trials with overweight and obese adults (55, 56, 57) using different treatment doses (100 to 400 mg/d) and duration (up to 24 weeks)

The protective caps at the ends of chromosomes that shrink with each cell division are called telomeres, and telomerase is in charge of preserving and lengthening them

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