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In the current study, the estimated measured levels of APAP were indicative of reaching toxicity levels, as previously reported by The present data based on APAP-induced hepatotoxicity in mice identified that PA treatment for 7 days at a dose of 200 mg/kg/day has critical actions in modulating APAP-induced liver toxicity in mice

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The combined anti-inflammatory and antioxidant effects converge to achieve chondroprotection (Figure 2)