The enzymatic oxidation is catalyzed by a family of enzymes, such as cytochrome P450 (CYP), cyclo-oxygenase-2 (COX-2), peroxidase, tyrosinase (monophenol oxygenase), xanthine oxidase (XO), monoamine oxidase (MAO), and polyphenol oxidases (PPO), and is a reversible reaction using reducing agents such as H 2 or H 2 S [164]
Diabetes mellitus increases risk of incident dementia in APOEvarepsilon4 carriers: A meta-analysis
10.1146/annurev.pharmtox.44.101802.121704 66
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The role of oxidative stress in the activation and function of immune cells is also critical in autoimmune diseases [133]