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These findings demonstrate that Gipr Syn/ mice are resistant to the weight-lowering effects of mGIPR-Ab, highlighting the crucial role of CNS GIPR for the body weight response to mGIPR-Ab

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Overall, the resolvable range of the Ycf1 R-domain coincides with the region containing the highest sequence conservation to CFTR, which possesses a longer R-domain than Ycf1 but otherwise conserved kinase motifs (Fig

[DOI] [PubMed] [Google Scholar] 49.Giana G., Romano E., Porfirio M.C., DAmbrosio R., Giovinazzo S., Troianiello M., Barlocci E., Travaglini D., Granstrem O., Pascale E., et al