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Further cardiovascular benefits of GLP-1 medications Interesting research about the symptomatic benefits of semaglutide in heart failure patients In patients with heart failure with preserved ejection fraction and obesity, treatment with semaglutide (2.4 mg) led to larger reductions in symptoms and physical limitations, greater improvements in exercise function, and greater weight loss than placebo Will future NICE guidance change to reflect this and advise on prescribing semaglutide for these patients