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These adducts were only detected in ESA-treated cells and were significantly reduced in ACSL1 -knockdown cells, demonstrating an ACSL1-dependent formation of oxidative adducts of ESA-derived acyl chains in neutral lipids

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The spinal action of BPC-157 on attenuates the acute nociceptive processing, but it has little effect facilitated component of the response evoked by persistent small afferent input