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Since your body only absorbs what you need, vitamin B12 does not have an upper limit (UL) which is the maximum amount of a vitamin you can take without side effects

This is due to the liver taking up all the circulating FFAs, which then interfere with insulin and IGF-1 signalling (as described above) and eventually leading to hepatic steatosis

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10.1128/aem.67.6.2718-2722.2001 3 AmachiS.KasaharaM.FujiiT.ShinoyamaH.HanadaS.KamagataY.et al (2004)

GHK-Cu modulates matrix genes in a model is a mechanistic finding