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In patients with suspected cobalamin hypersensitivity, consider administering an intradermal test dose of parenteral vitamin B12 prior to use of Cyanocobalamin Nasal Spray [see Warnings and Precautions (5.2)]

It also recycles other antioxidants, such as glutathione (GSH), and vitamins C and E, thereby enhancing their antioxidant capacities and repairing oxidative damage (Figure 2) [14,68,73]

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The Chaperokine Activity of Heat Shock Proteins